Headache and Comorbidities in Childhood and Adolescence by Vincenzo Guidetti Marco A. Arruda & Aynur Ozge

Author:Vincenzo Guidetti, Marco A. Arruda & Aynur Ozge
Language: eng
Format: epub
Publisher: Springer International Publishing, Cham

11.7 Conclusions

Migraine headaches and postictal headaches, particularly as part of specific epilepsy syndromes, are common among children and adolescents with epilepsy. Conversely, epileptic seizures occurring during migraine attacks are not rare. Both epilepsy and migraine share common mechanisms of action, and more common pathophysiologic phenomena are likely to be uncovered in the near future. Genetic defects, especially channelopathies, are probably responsible for most of the overlapping symptomatology of migraine and epilepsy and for the relative success of broad-spectrum antiepileptic drugs such as topiramate and valproate in preventing both seizures and migraine attacks. As our understanding of the mechanisms underlying migraine and epilepsy broadens, new and exciting therapeutic modalities will no doubt enhance therapeutic armamentarium.

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